Neo40 Professional

Nitric Oxide (NO) is critical for cardiovascular health. If you are looking for a Functional Medicine approach to cardiovascular disease then you simply can’t overlook Neo40 Professional.

We’ve been using and recommending Neo40 for the past year and we’ve had great results. The product was developed by Nathan Bryan, PhD who is one of the World’s experts in Nitric Oxide. This product has clinical trials showing improvement in Nitric Oxide (NO).

The problem is that there are 2 different versions: Neo40 and Neo40 Professional. The professional version is quite a bit more expensive and many of our patients found Neo40 online for less money so they purchased it there.

We try very hard to provide the highest quality at the lowest cost so that was frustrating to us and made us look in to what was going on.

We discovered that they were actually getting the regular Neo40 and not Neo40 Professional. So we looked into the difference between the 2. Neo40 Professional contains 5-MTHF (folate) 400mcg whereas the regular Neo40 does not. Neo40 Professional also has 425mg of their “proprietary Nitric Oxide blend” and the regular Neo40 only has 420mg.

That doesn’t seem like much of a difference to me. We have several other sources of 5-MTHF that we use so we aren’t missing that one at all. And 5mg difference in the “proprietary Nitric Oxide Blend” seems ridiculous so we made the decision to switch from recommending the professional version to the regular version.

We called HumanN, the manufacturer, to place our order and they told us that we shouldn’t make that switch. They transferred us to their scientific department so that we could talk with one of their scientists.

We told them that we didn’t need the 5-MTHF most of the time so that wasn’t so much of an issue. He then informed us that the extra 5mg of the “Proprietary Nitric Oxide Blend” showed a 20-25% increase in Nitric Oxide (NO) production. That little milligram difference makes a big difference in outcomes.

He went on to tell us that it really isn’t any cheaper to use the regular Neo40 because this is the package and dosing for ‘maintenance dosing.’ We should be using Neo40 twice daily for 1-2 months then switching to once daily after that. So, maintenance is 1 wafer per day if using either the regular Neo40 or Neo40 Professional.

MSRP of Neo40 (regular) is $39.95 for 30 wafers. That is $1.33 per wafer.

Now, Neo40 Profession MSRP is $99 for 60 wafers. That is $1.65 per wafer. Sometimes you can find it for $85 a box, $1.42 per wafer. Neo40 Professional is slightly more expensive ($0.09 per wafer) than the regular but the effect is substantially better.

We’ll stick with the professional version.